Trial | NCT00596024  Report issue

Title

Lutein and Alzheimer's Disease Study
Lutein and Oxidative Stress in Alzheimer's Disease - A Pilot Study

  • Phase

    Phase 2

  • Study Type

    Interventional

  • Status

    Terminated

  • Study Participants

    3
Oxidative damage by free radicals may be involved in causing Alzheimer's disease (AD). Free radicals may lead to death of nerve cells and decline in brain function. Certain antioxidants may suppress this free radical damage associated with AD. Carotenoids are a family of naturally occurring antioxidants that have important functions for human health. Carotenoids are known to reduce oxidative damage, but their effects have not been studied in AD patients.

The objective of the study is to examine whether lutein supplementation helps to reduce oxidative damage from free radicals in AD patients.
Study Started
Dec 31
2007
Primary Completion
Jul 31
2009
Study Completion
Jul 31
2009
Last Update
Aug 12
2019

Dietary Supplement lutein/zeaxanthin [lutein, zeaxanthin]

daily supplementation of lutein and zeaxanthin at dose of 12 mg/day

Dietary Supplement placebo

placebo capsules with the same size and coating as those of lutein/zeaxanthin supplements without active ingredients

1 Experimental

Daily Lutein/zeaxanthin supplementation with a meal

2 Placebo Comparator

Criteria 

Inclusion Criteria:

Diagnosed with moderately severe Alzheimer's disease
No Results Posted