Trial | NCT00565396  Report issue

Title

Effectiveness Study on Fosinopril and/or Losartan in Patients With Chronic Kidney Disease Stage 3
Multi-Center,Double-Blind,Randomized,Controlled Clinical Trial of Fosinopril and/or Losartan in Patients With Chronic Kidney Disease Stage 3

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Unknown status

  • Study Participants

    400
The purpose of this study is to determine whether fosinopril and losartan are effective in the treatment of patients with Chronic Kidney Disease(CKD) stage 3.
Study Started
Sep 30
2004
Study Completion
Jul 31
2008
Anticipated
Last Update
Nov 30
2007
Estimate

Drug Fosinopril and Losartan

Fosinopril 10mg/day(oral) Losartan 50mg/day(oral)

1 Active Comparator

Fosinopril 10mg/day(oral)

2 Active Comparator

Fosinopril 20mg/day(oral)

3 Active Comparator

Losartan 50mg/day(oral)

4 Active Comparator

Losartan 100mg/day(oral)

Criteria 

Inclusion Criteria:

Patients aged 18-75 years old
Roll out secondary renal diseases
Do not use steroids and immunosuppresive drugs
ACEI/ARB treated patients should have 7-14 days wash out period，SiDBP< 110mmHg
Willing and able to comprehend and give written informed consent
Willing to follow-up regularly

Exclusion Criteria:

Use steroids and immunosuppresive drugs
Secondary renal diseases
Acute cardio-cerebral diseases within 6 months
Post renal transplantation
Pregnant/Nursing women
History of hypersensitivity to ACEI/ARB
Refuse to join clinical trial
No Results Posted