Trial | NCT00469131  Report issue

Title

Effects of Immunosuppression on HCV Recurrence After Living Donor Liver Transplantation - Comparative Study Between Tacrolimus + MMF and Tacrolimus + Steroid
Randomized Comparative Study on Effects of Immunosuppression on HCV Recurrence After Living Donor Liver Transplantation - Comparison Between Tacrolimus + MMF and Tacrolimus + Steroid

  • Phase

    Phase 3

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    79
The aim of this study is to compare immunosuppression protocol of tacrolimus + MMF with that of tacrolimus + steroid for preventing recurrence of hepatitis C after living donor liver transplantation.
Study Started
Sep 30
2003
Primary Completion
Aug 31
2010
Study Completion
Aug 31
2011
Last Update
Sep 14
2011
Estimate

Drug tacrolimus + steroid

Drug tacrolimus + mycophenolate mofetil

1 Drug: Active Comparator

tacrolimus + steroid

2 Drug: Active Comparator

tacrolimus + mycophenolate mofetil

Criteria 

Inclusion Criteria:

Recipient of living donor liver transplantation for HCV-related cirrhosis

Exclusion Criteria:

ABO blood type incompatible transplant case
Renal dysfunction (serum creatinine >2.0 mg/dL)
WBC < 1,000/mm3
Hemoglobin < 8 g/dL
Platelet <30,000 /mm3
No Results Posted