Trial | NCT00342381  Report issue

Title

Fatigue in Multiple Sclerosis: Evaluated With 3 MRI and Transcranial Magnetic Stimulation
Fatigue in Multiple Sclerosis: Evaluated With 3 Tesla MRI and Transcranial Magnetic Stimulation

  • Phase

    Phase 2

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    120
The purpose of this study is to investigate fatigue in patients with multiple sclerosis (MS) and to determine the correlation between the symptom and cerebral changes.
Only recruiting from:

Department of Neurology, Aarhus University Hospital, Denmark
Study Started
Jun 30
2006
Study Completion
Dec 31
2007
Last Update
Dec 17
2007
Estimate

Drug 3,4-diaminopyridine

Single dose 3,4 diaminopyridine

Drug Placebo

Single dose placebo treatment

  • Other names: n/d

3.4 diaminopyridine Active Comparator

Single dose 3,4 diaminopyridine

Placebo Placebo Comparator

Two tablets identical to active treatment

Criteria 

Inclusion Criteria:

Relapsing remitting-multiple sclerosis (RR-MS) according to Poser criteria
EDSS: max 3.5
Right handed
Normal function of the right hand

Exclusion Criteria:

Disease interfering with MS
Known dementia
Drug or alcohol abuse
Treatment with psychoactive drugs within one week before study entry
Major changes of medical treatment within 3 weeks before study entry
Attack within 4 weeks before study entry
Pregnancy
Conditions interfering with 3,4-diaminopyridine treatment
Conditions interfering with MRI
Conditions interfering with transcranial magnetic stimulation
No Results Posted