Trial | NCT00311870  Report issue

Title

Renoprotective Effect of Nisoldipine and Lisinopril in Type 1 Diabetic Nephropathy

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    52
The aim of the study was to compare the renoprotective effect of a long acting calcium antagonist (nisoldipine) with an angiotensin converting enzyme inhibitor (lisinopril)in type 1 diabetic patients with diabetic kidney disease. In total, 51 patients were randomised to treatment with one of these drugs for 4 years. Changes in kidney function, blood pressure and urinary excretion of albumin were measured every 6 months
Study Started
Mar 31
1993
Study Completion
Apr 30
1999
Last Update
Apr 06
2006
Estimate

Drug nisoldipine

Drug lisinopril

Criteria 

Inclusion Criteria:

diabetic nephropathy, type 1 diabetes, hypertension

Exclusion Criteria:

child bearing potential, non-diabetic kidney disease, malignancy
No Results Posted