Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » Membrane Transport Proteins » Ion Pumps » Symporters » Sodium-Potassium-Chloride Symporters » Solute Carrier Family 12, Member 1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » Membrane Transport Proteins » Solute Carrier Proteins » Sodium-Potassium-Chloride Symporters » Solute Carrier Family 12, Member 1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Membrane Transport Proteins » Ion Pumps » Symporters » Sodium-Potassium-Chloride Symporters » Solute Carrier Family 12, Member 1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Membrane Transport Proteins » Solute Carrier Proteins » Sodium-Potassium-Chloride Symporters » Solute Carrier Family 12, Member 1
Description
Na-K-Cl transporter in the ASCENDING LIMB OF LOOP OF HENLE. It mediates active reabsorption of sodium chloride and is inhibited by LOOP DIURETICS such as FUROSEMIDE; and BUMETANIDE. Mutations in the gene encoding SLC12A1 are associated with a BARTTER SYNDROME. MeSH
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