Sodium Potassium Chloride Symporter Inhibitors D049994

Chemicals and Drugs [D] » Chemical Actions and Uses [D27] » Pharmacologic Actions » Molecular Mechanisms of Pharmacological Action » Membrane Transport Modulators » Sodium Potassium Chloride Symporter Inhibitors

Chemicals and Drugs [D] » Chemical Actions and Uses [D27] » Pharmacologic Actions » Physiological Effects of Drugs » Natriuretic Agents » Diuretics » Sodium Potassium Chloride Symporter Inhibitors

Description

Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA.   MeSH

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