Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Isomerases » Intramolecular Oxidoreductases » Carbon-Carbon Double Bond Isomerases » Dodecenoyl-CoA Isomerase » Peroxisomal Bifunctional Enzyme
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Lyases » Carbon-Oxygen Lyases » Hydro-Lyases » Enoyl-CoA Hydratase » Peroxisomal Bifunctional Enzyme
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Multifunctional Enzymes » Peroxisomal Bifunctional Enzyme
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Oxidoreductases » Alcohol Oxidoreductases » NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases » 3-Hydroxyacyl CoA Dehydrogenases » 3-Hydroxyacyl-CoA Dehydrogenase » Peroxisomal Bifunctional Enzyme
Description
A monomeric protein found in liver peroxisomes that contains two enzymatically active domains; an enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase domain, and an (S)-3-hydroxyacyl-CoA dehydrogenase domain. The enzyme is stereospecific with regards to how cis and trans double bonds are metabolized. It is complemented by PEROXISOMAL MULTIFUNCTIONAL PROTEIN-2, which has the opposite stereospecificity. MeSH
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