Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Blood Proteins » Immunoproteins » Immunoglobulins » Antibodies » Antibodies, Monoclonal » Antibodies, Monoclonal, Humanized
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Blood Proteins » Serum Globulins » Immunoglobulins » Antibodies » Antibodies, Monoclonal » Antibodies, Monoclonal, Humanized
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Globulins » Serum Globulins » Immunoglobulins » Antibodies » Antibodies, Monoclonal » Antibodies, Monoclonal, Humanized
Description
Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant region and part of the variable region are replaced, they are called humanized. If only the constant region is modified they are called chimeric. INN names for humanized antibodies end in -zumab. MeSH
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Subtype Terms (21)
Adalimumab
3 drugs (2 approved, 1 experimental)
Alemtuzumab
1 approved drug
Bevacizumab
17 drugs (11 approved, 6 experimental)
Nivolumab
1 approved drug
Omalizumab
1 approved drug
Ranibizumab
1 approved drug
Trastuzumab
1 approved drug
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