Related MeSH Hierarchy (8)
Chemicals and Drugs [D] » Macromolecular Substances [D05] » Polymers » Polyethylene Glycols » Certolizumab Pegol
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Peptide Fragments » Immunoglobulin Fragments » Immunoglobulin Fab Fragments » Certolizumab Pegol
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Blood Proteins » Immunoproteins » Immunoglobulins » Antibodies » Antibodies, Monoclonal » Antibodies, Monoclonal, Humanized » Certolizumab Pegol
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Blood Proteins » Immunoproteins » Immunoglobulins » Immunoglobulin Fragments » Immunoglobulin Fab Fragments » Certolizumab Pegol
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Blood Proteins » Serum Globulins » Immunoglobulins » Antibodies » Antibodies, Monoclonal » Antibodies, Monoclonal, Humanized » Certolizumab Pegol
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Blood Proteins » Serum Globulins » Immunoglobulins » Immunoglobulin Fragments » Immunoglobulin Fab Fragments » Certolizumab Pegol
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Globulins » Serum Globulins » Immunoglobulins » Antibodies » Antibodies, Monoclonal » Antibodies, Monoclonal, Humanized » Certolizumab Pegol
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Globulins » Serum Globulins » Immunoglobulins » Immunoglobulin Fragments » Immunoglobulin Fab Fragments » Certolizumab Pegol
Description
A polyethylene-glycolated Fab' fragment of TUMOR NECROSIS FACTOR antibody that binds specifically to TNF-ALPHA and neutralises it in a dose-dependent manner. It also inhibits the production of lipopolysaccharide-induced TNF-ALPHA and IL-1 BETA and is used to treat RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS. MeSH
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