Chemicals and Drugs [D] » Lipids [D10] » Lipoproteins » Lipoproteins, HDL » High-Density Lipoproteins, Pre-beta
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Lipoproteins » Lipoproteins, HDL » High-Density Lipoproteins, Pre-beta
Description
A highly dense subclass of the high-density lipoproteins, with particle sizes below 7 nm. They are also known as nascent HDL, composed of a few APOLIPOPROTEIN A-I molecules which are complexed with PHOSPHOLIPIDS. The lipid-poor pre-beta-HDL particles serve as progenitors of HDL3 and then HDL2 after absorption of free cholesterol from cell membranes, cholesterol esterification, and acquisition of apolipoproteins A-II, Cs, and E. Pre-beta-HDL initiate the reverse cholesterol transport process from cells to liver. MeSH
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