Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Ligases » Ubiquitin-Protein Ligase Complexes » Ubiquitin-Protein Ligases » Proto-Oncogene Proteins c-mdm2
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Neoplasm Proteins » Oncogene Proteins » Proto-Oncogene Proteins » Proto-Oncogene Proteins c-mdm2
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Nuclear Proteins » Proto-Oncogene Proteins c-mdm2
Description
An E3 UBIQUITIN LIGASE that interacts with and inhibits TUMOR SUPPRESSOR PROTEIN P53. Its ability to ubiquitinate p53 is regulated by TUMOR SUPPRESSOR PROTEIN P14ARF. MeSH
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