Related MeSH Hierarchy (5)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Intracellular Signaling Peptides and Proteins » Adaptor Proteins, Signal Transducing » Paxillin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » Adaptor Proteins, Signal Transducing » Paxillin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Adaptor Proteins, Signal Transducing » Paxillin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » LIM Domain Proteins » Paxillin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Phosphoproteins » Paxillin
Description
Paxillin is a signal transducing adaptor protein that localizes to FOCAL ADHESIONS via its four LIM domains. It undergoes PHOSPHORYLATION in response to integrin-mediated CELL ADHESION, and interacts with a variety of proteins including VINCULIN; FOCAL ADHESION KINASE; PROTO-ONCOGENE PROTEIN PP60(C-SRC); and PROTO-ONCOGENE PROTEIN C-CRK. MeSH
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