Anatomy [A] » Cells [A11] » Cellular Structures » Cell Membrane » Cell Membrane Structures » Cell-Matrix Junctions » Focal Adhesions
Description
An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of the ACTIN CYTOSKELETON terminate and attach to the transmembrane linkers, INTEGRINS, which in turn attach through their extracellular domains to EXTRACELLULAR MATRIX PROTEINS. MeSH
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