Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » Protein Serine-Threonine Kinases » MAP Kinase Kinase Kinases » raf Kinases
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Transferases » Phosphotransferases » Phosphotransferases (Alcohol Group Acceptor) » Protein Kinases » Protein Serine-Threonine Kinases » MAP Kinase Kinase Kinases » raf Kinases
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Neoplasm Proteins » Oncogene Proteins » Proto-Oncogene Proteins » raf Kinases
Description
A family of closely-related serine-threonine kinases that were originally identified as the cellular homologs of the retrovirus-derived V-RAF KINASES. They are MAP kinase kinase kinases that play important roles in SIGNAL TRANSDUCTION. MeSH
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Subtype Terms (4)
Proto-Oncogene Proteins B-raf
29 drugs (23 approved, 6 experimental)
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