Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Neoplasm Proteins » Oncogene Proteins » Proto-Oncogene Proteins » Receptors, Thyroid Hormone » Thyroid Hormone Receptors beta
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Receptors, Cytoplasmic and Nuclear » Receptors, Thyroid Hormone » Thyroid Hormone Receptors beta
Description
High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRB gene (also known as NR1A2, THRB1, or ERBA2 gene) as several isoforms produced by alternative splicing. Mutations in the THRB gene cause THYROID HORMONE RESISTANCE SYNDROME. MeSH
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