Phenomena and Processes [G] » Genetic Phenomena [G05] » Gene Expression Regulation » Epigenesis, Genetic » Gene Silencing » RNA Interference
Description
A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process. MeSH
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