Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Hydrolases » Peptide Hydrolases » Cathepsins » Cathepsin C
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Hydrolases » Peptide Hydrolases » Cysteine Proteases » Cathepsin C
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Hydrolases » Peptide Hydrolases » Exopeptidases » Dipeptidyl-Peptidases and Tripeptidyl-Peptidases » Cathepsin C
Description
A papain-like cysteine protease that has specificity for amino terminal dipeptides. The enzyme plays a role in the activation of several pro-inflammatory serine proteases by removal of their aminoterminal inhibitory dipeptides. Genetic mutations that cause loss of cathepsin C activity in humans are associated with PAPILLON-LEFEVRE DISEASE. MeSH
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