Related MeSH Hierarchy (6)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Membrane Transport Proteins » Ion Pumps » Anion Transport Proteins » Organic Anion Transporters » Organic Anion Transporters, ATP-Dependent » ATP Binding Cassette Transporter, Subfamily B » ATP Binding Cassette Transporter, Subfamily B, Member 1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » Membrane Transport Proteins » ATP-Binding Cassette Transporters » ATP Binding Cassette Transporter, Subfamily B » ATP Binding Cassette Transporter, Subfamily B, Member 1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » Membrane Transport Proteins » Ion Pumps » Anion Transport Proteins » Organic Anion Transporters » Organic Anion Transporters, ATP-Dependent » ATP Binding Cassette Transporter, Subfamily B » ATP Binding Cassette Transporter, Subfamily B, Member 1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Glycoproteins » Membrane Glycoproteins » ATP-Binding Cassette Transporters » ATP Binding Cassette Transporter, Subfamily B » ATP Binding Cassette Transporter, Subfamily B, Member 1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Membrane Glycoproteins » ATP-Binding Cassette Transporters » ATP Binding Cassette Transporter, Subfamily B » ATP Binding Cassette Transporter, Subfamily B, Member 1
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Membrane Transport Proteins » ATP-Binding Cassette Transporters » ATP Binding Cassette Transporter, Subfamily B » ATP Binding Cassette Transporter, Subfamily B, Member 1
Description
A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE). MeSH
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Phase 1 Indicated Drugs (1)
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