Chemicals and Drugs [D] » Organic Chemicals [D02] » Lactones » Macrolides » Sirolimus
Description
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties. MeSH
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Subtype Terms (1)
Everolimus
5 drugs (4 approved, 1 experimental)
Phase 1 Indicated Drugs (1)
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