Chemicals and Drugs [D] » Organic Chemicals [D02] » Lactones » Macrolides
Chemicals and Drugs [D] » Organic Chemicals [D02] » Lactones » Polyketides » Macrolides
Chemicals and Drugs [D] » Polycyclic Compounds [D04] » Macrocyclic Compounds » Polyketides » Macrolides
Description
A group of often glycosylated macrocyclic compounds formed by chain extension of multiple PROPIONATES cyclized into a large (typically 12, 14, or 16)-membered lactone. Macrolides belong to the POLYKETIDES class of natural products, and many members exhibit ANTIBIOTIC properties. MeSH
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Subtype Terms (23)
Fidaxomicin
2 approved drugs
Ivermectin
1 approved drug
Sirolimus
1 approved drug
Tacrolimus
5 approved drugs
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