Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » Membrane Transport Proteins » Ion Channels » Calcium Channels » Ryanodine Receptor Calcium Release Channel
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Contractile Proteins » Muscle Proteins » Ryanodine Receptor Calcium Release Channel
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Membrane Glycoproteins » Ion Channels » Calcium Channels » Ryanodine Receptor Calcium Release Channel
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Membrane Transport Proteins » Ion Channels » Calcium Channels » Ryanodine Receptor Calcium Release Channel
Description
A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES. MeSH
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