Chemicals and Drugs [D] » Organic Chemicals [D02] » Hydrocarbons » Terpenes » Diterpenes » Ryanodine
Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Alkaloids » Ryanodine
Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Heterocyclic Compounds, 1-Ring » Azoles » Pyrroles » Ryanodine
Description
A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM. MeSH
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