Diseases [C] » Neoplasms [C04] » Neoplasms by Histologic Type » Neoplasms, Germ Cell and Embryonal » Mesonephroma » Endodermal Sinus Tumor
Description
An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumor found in children. It is characterized by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (Schiller-Duval body). The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1189) MeSH
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Phase 1 Indicated Drugs (4)
Organization Involved with Phase 3 Indications (8)
Organization Involved with Phase 2 Indications (1)
Organization Involved with Phase 1 Indications (2)
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UMLS Data
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