Chemicals and Drugs [D] » Organic Chemicals [D02] » Lactones » Polyketides » Macrolides » Erythromycin » Clarithromycin
Description
A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation. MeSH
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