Glycation End Products, Advanced D017127

Chemicals and Drugs [D] » Carbohydrates [D09] » Glycoconjugates » Glycation End Products, Advanced

Chemicals and Drugs [D] » Biological Factors [D23] » Toxins, Biological » Glycation End Products, Advanced

Description

A heterogeneous group of compounds derived from rearrangements, oxidation, and cross-linking reactions that follow from non-enzymatic glycation of amino groups in PROTEINS; LIPIDS; or NUCLEIC ACIDS. Their accumulation in vivo accelerates under hyperglycemic, oxidative, or inflammatory conditions. Heat also accelerates the formation of advanced glycation end products (AGEs) such seen with the browning of food during cooking.   MeSH

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