Oncogene Protein p21(ras) D015689

Related MeSH Hierarchy (6)

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » GTP-Binding Proteins » Monomeric GTP-Binding Proteins » ras Proteins » Oncogene Protein p21(ras)

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Viral Proteins » Oncogene Proteins, Viral » Retroviridae Proteins, Oncogenic » Oncogene Protein p21(ras)

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Viral Proteins » Retroviridae Proteins » Retroviridae Proteins, Oncogenic » Oncogene Protein p21(ras)

Description

Transforming protein encoded by ras oncogenes. Point mutations in the cellular ras gene (c-ras) can also result in a mutant p21 protein that can transform mammalian cells. Oncogene protein p21(ras) has been directly implicated in human neoplasms, perhaps accounting for as much as 15-20% of all human tumors. This enzyme was formerly listed as EC 3.6.1.47.   MeSH

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