Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Intracellular Signaling Peptides and Proteins » GTP-Binding Proteins » Monomeric GTP-Binding Proteins » ras Proteins
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Hydrolases » Acid Anhydride Hydrolases » GTP Phosphohydrolases » GTP-Binding Proteins » Monomeric GTP-Binding Proteins » ras Proteins
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » GTP-Binding Proteins » Monomeric GTP-Binding Proteins » ras Proteins
Description
Small, monomeric GTP-binding proteins encoded by ras genes (GENES, RAS). The protooncogene-derived protein, PROTO-ONCOGENE PROTEIN P21(RAS), plays a role in normal cellular growth, differentiation and development. The oncogene-derived protein ONCOGENE PROTEIN P21(RAS) can play a role in aberrant cellular regulation during neoplastic cell transformation (CELL TRANSFORMATION, NEOPLASTIC). This enzyme was formerly listed as EC 3.6.1.47. MeSH
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Subtype Terms (2)
Proto-Oncogene Proteins p21(ras)
10 drugs (7 approved, 3 experimental)
Phase 3 Indicated Drugs (5)
Phase 2 Indicated Drugs (19)
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