Related MeSH Hierarchy (17)
Diseases [C] » Otorhinolaryngologic Diseases [C09] » Ear Diseases » Hearing Disorders » Hearing Loss » Deafness » Deaf-Blind Disorders » Wolfram Syndrome
Diseases [C] » Nervous System Diseases [C10] » Cranial Nerve Diseases » Optic Nerve Diseases » Optic Atrophy » Optic Atrophies, Hereditary » Wolfram Syndrome
Diseases [C] » Nervous System Diseases [C10] » Neurodegenerative Diseases » Heredodegenerative Disorders, Nervous System » Optic Atrophies, Hereditary » Wolfram Syndrome
Diseases [C] » Nervous System Diseases [C10] » Neurologic Manifestations » Sensation Disorders » Hearing Disorders » Hearing Loss » Deafness » Deaf-Blind Disorders » Wolfram Syndrome
Diseases [C] » Nervous System Diseases [C10] » Neurologic Manifestations » Sensation Disorders » Vision Disorders » Blindness » Deaf-Blind Disorders » Wolfram Syndrome
Diseases [C] » Eye Diseases [C11] » Eye Diseases, Hereditary » Optic Atrophies, Hereditary » Wolfram Syndrome
Diseases [C] » Eye Diseases [C11] » Optic Nerve Diseases » Optic Atrophy » Optic Atrophies, Hereditary » Wolfram Syndrome
Diseases [C] » Eye Diseases [C11] » Vision Disorders » Blindness » Deaf-Blind Disorders » Wolfram Syndrome
Diseases [C] » Urogenital Diseases [C12] » Female Urogenital Diseases and Pregnancy Complications » Female Urogenital Diseases » Urologic Diseases » Kidney Diseases » Diabetes Insipidus » Wolfram Syndrome
Diseases [C] » Urogenital Diseases [C12] » Male Urogenital Diseases » Urologic Diseases » Kidney Diseases » Diabetes Insipidus » Wolfram Syndrome
Diseases [C] » Urogenital Diseases [C12] » Urologic Diseases » Kidney Diseases » Diabetes Insipidus » Wolfram Syndrome
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Congenital Abnormalities » Abnormalities, Multiple » Deaf-Blind Disorders » Wolfram Syndrome
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Eye Diseases, Hereditary » Optic Atrophies, Hereditary » Wolfram Syndrome
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Heredodegenerative Disorders, Nervous System » Optic Atrophies, Hereditary » Wolfram Syndrome
Diseases [C] » Nutritional and Metabolic Diseases [C18] » Metabolic Diseases » Glucose Metabolism Disorders » Diabetes Mellitus » Diabetes Mellitus, Type 1 » Wolfram Syndrome
Diseases [C] » Endocrine System Diseases [C19] » Diabetes Mellitus » Diabetes Mellitus, Type 1 » Wolfram Syndrome
Diseases [C] » Endocrine System Diseases [C19] » Pituitary Diseases » Diabetes Insipidus » Wolfram Syndrome
Description
A hereditary condition characterized by multiple symptoms including those of DIABETES INSIPIDUS; DIABETES MELLITUS; OPTIC ATROPHY; and DEAFNESS. This syndrome is also known as DIDMOAD (first letter of each word) and is usually associated with VASOPRESSIN deficiency. It is caused by mutations in gene WFS1 encoding wolframin, a 100-kDa transmembrane protein. MeSH
Hierarchy View
Phase 2 Indicated Drugs (4)
Other Experimental Indicated Drugs (1)
Organization Involved with Phase 3 Indications (1)
Organization Involved with Phase 2 Indications (2)
Hierarchy Tree View
UMLS Data
YOU AGREE THAT THE INFORMATION PROVIDED ON THIS WEBSITE IS PROVIDED “AS IS”, WITHOUT ANY WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING WITHOUT LIMITATION WARRANTIES OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE, OR NON-INFRINGEMENT OF ANY THIRD-PARTY PATENT, COPYRIGHT, OR ANY OTHER THIRD-PARTY RIGHT. IN NO EVENT SHALL THE CREATORS OF THE WEBSITE OR WASHINGTON UNIVERSITY BE LIABLE FOR ANY DIRECT, INDIRECT, SPECIAL, OR CONSEQUENTIAL DAMAGES ARISING OUT OF OR IN ANY WAY CONNECTED WITH THE WEBSITE, THE USE OF THE WEBSITE, OR THIS AGREEMENT, WHETHER IN BREACH OF CONTRACT, TORT OR OTHERWISE, EVEN IF SUCH PARTY IS ADVISED OF THE POSSIBILITY OF SUCH DAMAGES.
