Related MeSH Hierarchy (7)
Chemicals and Drugs [D] » Hormones, Hormone Substitutes, and Hormone Antagonists [D06] » Hormones » Peptide Hormones » Hypothalamic Hormones » Pro-Opiomelanocortin
Chemicals and Drugs [D] » Hormones, Hormone Substitutes, and Hormone Antagonists [D06] » Hormones » Peptide Hormones » Pituitary Hormones » Pituitary Hormones, Anterior » Pro-Opiomelanocortin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Neuropeptides » Hypothalamic Hormones » Pro-Opiomelanocortin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Peptide Hormones » Hypothalamic Hormones » Pro-Opiomelanocortin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Peptide Hormones » Pituitary Hormones » Pituitary Hormones, Anterior » Pro-Opiomelanocortin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Nerve Tissue Proteins » Neuropeptides » Hypothalamic Hormones » Pro-Opiomelanocortin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Protein Precursors » Pro-Opiomelanocortin
Description
A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP). MeSH
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Subtype Terms (9)
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