alpha-MSH D000521

Related MeSH Hierarchy (14)

Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Neuropeptides » Melanocyte-Stimulating Hormones » alpha-MSH

Description

A 13-amino acid peptide derived from proteolytic cleavage of ADRENOCORTICOTROPIC HORMONE, the N-terminal segment of ACTH. ACTH (1-13) is amidated at the C-terminal to form ACTH (1-13)NH2 which in turn is acetylated to form alpha-MSH in the secretory granules. Alpha-MSH stimulates the synthesis and distribution of MELANIN in MELANOCYTES in mammals and MELANOPHORES in lower vertebrates.   MeSH

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