Chemicals and Drugs [D] » Organic Chemicals [D02] » Carboxylic Acids » Acids, Acyclic » Caproates » Mycophenolic Acid
Chemicals and Drugs [D] » Lipids [D10] » Fatty Acids » Mycophenolic Acid
Description
Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase (IMP DEHYDROGENASE). Mycophenolic acid exerts selective effects on the immune system in which it prevents the proliferation of T-CELLS, LYMPHOCYTES, and the formation of antibodies from B-CELLS. It may also inhibit recruitment of LEUKOCYTES to sites of INFLAMMATION. MeSH
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Phase 4 Indicated Drugs (3)
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