Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Alkaloids » Opiate Alkaloids » Morphinans » Dextromethorphan
Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Heterocyclic Compounds, Bridged-Ring » Morphinans » Dextromethorphan
Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Heterocyclic Compounds, Fused-Ring » Heterocyclic Compounds, 4 or More Rings » Morphinans » Dextromethorphan
Chemicals and Drugs [D] » Polycyclic Compounds [D04] » Polycyclic Aromatic Hydrocarbons » Phenanthrenes » Morphinans » Dextromethorphan
Description
Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity. MeSH
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