Related MeSH Hierarchy (6)
Chemicals and Drugs [D] » Polycyclic Compounds [D04] » Macrocyclic Compounds » Peptides, Cyclic » Polymyxins » Colistin
Chemicals and Drugs [D] » Lipids [D10] » Lipopeptides » Polymyxins » Colistin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Antimicrobial Cationic Peptides » Polymyxins » Colistin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Peptides, Cyclic » Polymyxins » Colistin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Peptides » Antimicrobial Peptides » Antimicrobial Cationic Peptides » Polymyxins » Colistin
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Pore Forming Cytotoxic Proteins » Antimicrobial Cationic Peptides » Polymyxins » Colistin
Description
Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally. MeSH
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Phase 4 Indicated Drugs (1)
Other Experimental Indicated Drugs (1)
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