Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Alkaloids » Camptothecin
Description
An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity. MeSH
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Subtype Terms (2)
Irinotecan
5 approved drugs
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