Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Isomerases » DNA Topoisomerases » DNA Topoisomerases, Type I
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Nuclear Proteins » Poly-ADP-Ribose Binding Proteins » DNA Topoisomerases, Type I
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Carrier Proteins » Poly-ADP-Ribose Binding Proteins » DNA Topoisomerases, Type I
Description
DNA TOPOISOMERASES that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. DNA Topoisomerases, Type I enzymes reduce the topological stress in the DNA structure by relaxing the superhelical turns and knotted rings in the DNA helix. MeSH
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