Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Cytochromes » Cytochrome P-450 Enzyme System » Cytochrome P-450 CYP2J2
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Oxidoreductases » Oxygenases » Mixed Function Oxygenases » Cytochrome P-450 Enzyme System » Cytochrome P-450 CYP2J2
Chemicals and Drugs [D] » Lipids [D10] » Fatty Acids » Fatty Acids, Unsaturated » Cytochrome P-450 CYP2J2
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Hemeproteins » Cytochromes » Cytochrome P-450 Enzyme System » Cytochrome P-450 CYP2J2
Description
A cytochrome P450 enzyme involved in oxidizing POLYUNSATURATED FATTY ACIDS (PUFA) to PUFA epoxides which function as potent lipid mediators. This enzyme, encoded by CYP2J2 gene, metabolizes ARACHIDONIC ACID to epoxyeicosatrienoic acids (EETs) which produce biological effects including VASODILATION. MeSH
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