Active Ingredient History
Vinorelbine (trade name Navelbine) is a semi-synthetic vinca-alkaloid with a broad spectrum of anti-tumour activity. Vinorelbine is a mitotic spindle poison that impairs chromosomal segregation during mitosis. It blocks cells at G2/M. Microtubules (derived from polymers of tubulin) are the principal target of vinorelbine. Vinorelbine was developed by Pierre Fabre under licence from the CNRS in France. NAVELBINE (vinorelbine tartrate) as a single agent or in combination is indicated for the first line treatment of non small cell lung cancer and advanced breast cancer. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Breast Neoplasms (approved 1994)
Carcinoma, Non-Small-Cell Lung (approved 1994)
Adenocarcinoma (Phase 2)
Adenocarcinoma of Lung (Phase 3)
Adolescent (Phase 2)
Amyloidosis (Phase 2)
Brain Neoplasms (Phase 2)
Breast (Phase 1/Phase 2)
Breast Carcinoma In Situ (Phase 2)
Breast Diseases (Phase 2)
Breast Neoplasms (Phase 4)
Breast Neoplasms, Male (Phase 2)
Bronchial Neoplasms (Phase 3)
Carcinoma (Phase 2)
Carcinoma, Bronchogenic (Phase 3)
Carcinoma, Ductal, Breast (Phase 3)
Carcinoma, Islet Cell (Phase 1)
Carcinoma, Non-Small-Cell Lung (Phase 4)
Carcinoma, Renal Cell (Phase 1)
Carcinoma, Squamous Cell (Phase 3)
Chemoradiotherapy (Phase 2)
Child (Phase 2)
Choroidal Neovascularization (Phase 1)
Circulating Tumor DNA (Phase 2)
Cisplatin (Phase 2)
Colonic Neoplasms (Phase 2)
Colorectal Neoplasms (Phase 2)
Cytoreduction Surgical Procedures (Phase 2)
Desmoplastic Small Round Cell Tumor (Phase 1/Phase 2)
Diffuse Intrinsic Pontine Glioma (Phase 2)
Disease-Free Survival (Phase 2/Phase 3)
Disease Progression (Phase 2)
Drugs, Investigational (Phase 2)
Endometrial Neoplasms (Phase 1)
Epidermal Growth Factor (Phase 3)
Esophageal Neoplasms (Phase 3)
Esophageal Squamous Cell Carcinoma (Phase 3)
Fallopian Tube Neoplasms (Phase 2)
Fatigue (Phase 2)
Genetic Predisposition to Disease (Phase 3)
Glioma (Phase 2)
Hamartoma (Phase 2)
Head and Neck Neoplasms (Phase 2)
Hodgkin Disease (Phase 3)
Immunotherapy (Phase 2)
Inflammatory Breast Neoplasms (Phase 2)
Intestinal Neoplasms (Phase 1)
Kidney Neoplasms (Phase 2)
Leiomyosarcoma (Phase 1)
Leukemia (Phase 1/Phase 2)
Lung Diseases (Phase 3)
Lung Neoplasms (Phase 3)
Lymphoma (Phase 3)
Lymphoma, Large B-Cell, Diffuse (Phase 2)
Lymphoma, Large-Cell, Anaplastic (Phase 3)
Lymphoma, Large-Cell, Immunoblastic (Phase 1/Phase 2)
Lymphoma, Non-Hodgkin (Phase 3)
Lymphoma, T-Cell, Peripheral (Phase 2)
Medulloblastoma (Phase 2)
Melanoma (Phase 2)
Mesothelioma (Phase 3)
Mesothelioma, Malignant (Phase 3)
Multiple Myeloma (Phase 2)
Musculoskeletal Diseases (Phase 2)
Mutation (Phase 3)
Neoadjuvant Therapy (Phase 2)
Neoplasm Metastasis (Phase 3)
Neoplasms ()
Neoplasms, Connective and Soft Tissue (Phase 2)
Neuroblastoma (Phase 2)
Neuroendocrine Tumors (Phase 2)
Oncogene Proteins (Phase 2)
Osteosarcoma (Phase 2)
Ovarian Diseases (Phase 1/Phase 2)
Ovarian Neoplasms (Phase 2)
Pancreatic Neoplasms (Phase 2)
Pathology (Phase 2)
Pheochromocytoma (Phase 1)
Prostatic Neoplasms (Phase 2)
Radiation Oncology (Phase 2)
Radiotherapy (Phase 3)
Respiratory Tract Diseases (Phase 3)
Respiratory Tract Neoplasms (Phase 3)
Rhabdomyosarcoma (Phase 3)
Rhabdomyosarcoma, Alveolar (Phase 3)
Rhabdomyosarcoma, Embryonal (Phase 3)
Sarcoma (Phase 3)
Sarcoma, Ewing (Phase 2)
Small Cell Lung Carcinoma (Phase 1/Phase 2)
Stomach Neoplasms (Phase 2)
Thoracic Neoplasms (Phase 3)
Thymidylate Synthase (Phase 2)
Thyroid Neoplasms (Phase 1)
Triple Negative Breast Neoplasms (Phase 3)
Urinary Bladder Neoplasms (Phase 1)
Uterine Cervical Neoplasms (Phase 3)
Vaginal Neoplasms (Phase 1)
Vinorelbine (Phase 2)
Trial | Phase | Start Date | Organizations | Indications |
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