Active Ingredient History

NOW
  • Now
Vinorelbine (trade name Navelbine) is a semi-synthetic vinca-alkaloid with a broad spectrum of anti-tumour activity. Vinorelbine is a mitotic spindle poison that impairs chromosomal segregation during mitosis. It blocks cells at G2/M. Microtubules (derived from polymers of tubulin) are the principal target of vinorelbine. Vinorelbine was developed by Pierre Fabre under licence from the CNRS in France. NAVELBINE (vinorelbine tartrate) as a single agent or in combination is indicated for the first line treatment of non small cell lung cancer and advanced breast cancer.   NCATS

  • SMILES: CCC1=C[C@@H]2CN(C1)Cc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C)[C@H]7[C@](O)([C@H](OC(=O)C)[C@]8(CC)C=CCN9CC[C@]67[C@H]89)C(=O)OC
  • InChIKey: GBABOYUKABKIAF-IELIFDKJSA-N
  • Mol. Mass: 778.95
  • ALogP: 4.75
  • ChEMBL Molecules:
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Drug Pricing (per unit)

Australia

$7.8538 - $86.9732
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

5'-anhydrovinblastine | 5'-noranhydrovinblastine | 5'-nor-anhydrovinblastine | c'-norvincaleukoblastine, 3',4'-didehydro-4'-deoxy- | kw 2307 | kw-2307 | liposomal vinorelbine | navelbin | navelbine | navelbine base | nor-5'-anhydrovinblastine | noranhydrovinblastine tartrate | vinorelbin | vinorelbina | vinorelbin ditartrate | vinorelbine | vinorelbine base | vinorelbine ditartarate | vinorelbine ditartrate | vinorelbine (ditartrate) | vinorelbine ditartrate salt hydrate | vinorelbine tartrate | vinorelbinum

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