Active Ingredient History

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Amitriptyline is a derivative of dibenzocycloheptadiene and a tricyclic antidepressant (TCA) and is mainly used to treat symptoms of depression. It works on the central nervous system (CNS) by inhibiting the membrane pump mechanism responsible for uptake of norepinephrine and serotonin in adrenergic and serotonergic neurons. Amitriptyline has been frequently used as an active comparator in clinical trials on newer antidepressants. It is rarely used as a first-line antidepressant nowadays due to its high degree of toxicity in overdose and generally poorer tolerability than the newer antidepressants.   NCATS

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Drug Pricing (per unit)

United States

$0.0257 - $1.4646

Australia

$0.0425 - $0.0792
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

( amitriptyline (elavil), chlordiazepoxide (librium) - other name: limbitrol )
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( amitriptyline (elavil), perphenazine (trilafon) - other names: etrafon, etrafon-a, etrafon-forte )
10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5h-dibenzo(a,d)cycloheptene | 10,11-dihydro-n,n-dimethyl-5h-dibenzo(a,d)heptalene-delta(5),gamma-propylamine | 3-(10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5-ylidene)-n,n-dimethyl-1-propanamine | 3-(10,11-dihydro-5h-dibenzo[a,d]cyclohepten-5-ylidene)-n,n-dimethylpropan-1-amine | 5-(3-dimethylaminopropylidene)-10,11-dihydro-5h-dibenzo(a,d)cycloheptatriene | 5-(3-dimethylaminopropylidene)-10,11-dihydro-5h-dibenzo(a,d)cycloheptene | 5-(gamma-dimethylaminopropylidene)-5h-dibenzo[a,d][1,4]cycloheptadiene | amitid | amitril | amitriprolidine | amitriptilina | amitriptylin | amitriptyline | amitriptyline - chlordiazepoxide | amitriptyline, chlordiazepoxide drug combination | amitriptyline hcl | amitriptyline hydrochloride | amitriptyline hydrochloride, chlordiazepoxide drug combination | amitriptylinum | amitryptaline | amitryptiline | amitryptiline hcl | amitryptiline hydrochloride | cytriptyline | damitriptyline | domical | elavil | endep | etrafon-a | etrafon-forte | lentizol | limbitrol | limbitrol 5 | limbritol | saroten | saroten retard | triptafen | triptafen-m | tryptizol | tryptizol-75

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