Chemicals and Drugs [D] » Organic Chemicals [D02] » Hydrocarbons » Hydrocarbons, Cyclic » Hydrocarbons, Aromatic » Polycyclic Aromatic Hydrocarbons » Benzocycloheptenes » Dibenzocycloheptenes » Amitriptyline
Chemicals and Drugs [D] » Polycyclic Compounds [D04] » Polycyclic Aromatic Hydrocarbons » Benzocycloheptenes » Dibenzocycloheptenes » Amitriptyline
Description
Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines. MeSH
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Phase 3 Indicated Drugs (2)
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