Active Ingredient History

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Alogliptin (trade name Nesina in the US and Vipidia in Europe) is an orally administered anti-diabetic drug in the DPP-4 inhibitor class, discovered by Takeda Pharmaceutical Company's wholly owned subsidiary, Takeda San Diego, Inc. (former Syrrx) which was acquired by Takeda in 2005. Alogliptin does not decrease the risk of heart attack and stroke. Like other members of the gliptin class, it causes little or no weight gain, exhibits relatively little risk of causing hypoglycemia, and exhibits relatively modest glucose-lowering activity. Alogliptin and other gliptins are commonly used in combination with metformin in patients whose diabetes cannot adequately be controlled with metformin alone.   NCATS

  • SMILES: CN1C(=O)C=C(N2CCC[C@@H](N)C2)N(Cc3ccccc3C#N)C1=O
  • InChIKey: ZSBOMTDTBDDKMP-OAHLLOKOSA-N
  • Mol. Mass: 339.4
  • ALogP: 0.39
  • ChEMBL Molecules:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Oral
  • Pro Drug: No

Drug Pricing (per unit)

United States

$0.5300 - $13.0428
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

2-((6-((3r)-3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)methyl) benzonitrile | alogliptin | alogliptina | alogliptin benzoate | alogliptin benzoate / metformin hydrochloride | alogliptine | alogliptin / metformin | alogliptin / pioglitazone | alogliptinum | nesina | syr322 | syr 322 | syr-322 | vipidia

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