Active Ingredient History

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Amoxicillin is one of the widely prescribed antibacterial agents, which was discovered by scientists at Beecham Research Laboratories in 1972. In the US GlaxoSmithKline markets it under the original brand name Amoxil. It is the first line treatment for middle ear infections. It is also used for strep throat, pneumonia, skin infections, and urinary tract infections it is taken by mouth. Amoxicillin inhibits the third and final stage of bacterial cell wall synthesis by preferentially binding to specific penicillin-binding proteins (PBPs) that are located inside the bacterial cell wall. This results in a formation of defective cell wall and a cell death. Common side effects include nausea and rash. It may also increase the risk of yeast infections and, when used in combination with clavulanic acid, diarrhea. It should not be used in those who are allergic to penicillin.   NCATS

  • SMILES: CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O
  • InChIKey: LSQZJLSUYDQPKJ-NJBDSQKTSA-N
  • Mol. Mass: 365.41
  • ALogP: 0.02
  • ChEMBL Molecules:
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Drug Pricing (per unit)

United States

$0.0139 - $0.2572

Australia

$0.0612 - $5.3108
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

( clavulanate (Augmentin), amoxicillin - other names: augmentin '200', augmentin '250', augmentin '400', augmentin '500', augmentin '875', augmentin es, augmentin xr )
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( amoxicillin, clarithromycin (biaxin), lansoprazole (prevacid) - other name: lansoprazole, amoxicillin and clarithromycin (copackaged) )
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( amoxicillin, rifabutin (mycobutin), omeprazole (prilosec) - other name: omeprazole magnesium, amoxicillin, rifabutin )
amix 125 | amix 250 | amix 500 | amocillin | amocilline | amopen | amoram | amox | amoxacillin | amoxcillin | amoxicilina | amoxicillin | amoxicillin anhydrous | amoxicillin (anhydrous) | amoxicillin - ascorbic acid - niacinamide - riboflavin - thiamine | amoxicillin, ascorbic acid, niacinamide, riboflavin, thiamine drug combination | amoxicilline | amoxicillin hydrate | amoxicillin pediatric | amoxicillin sodium | amoxicillin trihydrate | amoxicillinum | amoxicllin | amoxident 250 | amoxident 500 | amoxi-inject | amoxil | amoxil fiztab | amoxil sf | amoxi-tabs | amoxycillin | amoxymed | amrit | aquacil | biomox | brl-2333 | brl-2333ab-b | combination of fosfomycin, metronidazole and rhgm-csf (administered together intraperitoneally) and three days of antibiotics p.o. | dedoxil | dispermox | flemoxin solutab | galenamox | iramox | larotid | moxacin | moxatag | polymox | respillin | robamox | sumox | trimox | utimox | vetremox | wymox | zoxycil 250 | zoxycil 500

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