Active Ingredient History
Amoxicillin is one of the widely prescribed antibacterial agents, which was discovered by scientists at Beecham Research Laboratories in 1972. In the US GlaxoSmithKline markets it under the original brand name Amoxil. It is the first line treatment for middle ear infections. It is also used for strep throat, pneumonia, skin infections, and urinary tract infections it is taken by mouth. Amoxicillin inhibits the third and final stage of bacterial cell wall synthesis by preferentially binding to specific penicillin-binding proteins (PBPs) that are located inside the bacterial cell wall. This results in a formation of defective cell wall and a cell death. Common side effects include nausea and rash. It may also increase the risk of yeast infections and, when used in combination with clavulanic acid, diarrhea. It should not be used in those who are allergic to penicillin. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Combination drugs
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Staphylococcal Skin Infections (approved 1980)
Abscess (Phase 3)
Acne Vulgaris (Phase 1)
Acute Coronary Syndrome (Phase 4)
Agammaglobulinemia (Phase 2/Phase 3)
Aggressive Periodontitis (Phase 1/Phase 2)
Allergy and Immunology (Phase 4)
Alveolar Bone Loss (Phase 4)
Amoxicillin (Phase 4)
Anti-Bacterial Agents (Phase 4)
Antibiotic Prophylaxis (Phase 4)
Appendicitis (Phase 4)
Arm Injuries (Phase 4)
Arthritis, Infectious (Phase 4)
Bacteremia (Phase 3)
Bacterial Infections (Phase 4)
Bismuth (Phase 4)
Bone Diseases, Infectious (Phase 4)
Bronchitis (Phase 4)
Buruli Ulcer (Phase 2)
Child Development (Phase 4)
Child Nutrition Disorders (Phase 4)
Chronic Periodontitis (Phase 4)
Colitis, Ulcerative (Phase 2)
Communicable Diseases (Phase 4)
Community-Acquired Infections (Phase 4)
COVID-19 (Phase 3)
Cystitis (Phase 3)
Cytochrome P-450 CYP2C19 (Phase 4)
Delivery, Obstetric (Phase 4)
Dental Pulp (Phase 4)
Diabetes Mellitus (Phase 3)
Diarrhea (Phase 4)
Disease Eradication (Phase 1)
Drug Resistance, Bacterial (Phase 4)
Drug Therapy (Phase 4)
Dry Socket (Phase 2)
Dyspepsia (Phase 4)
Endocarditis (Phase 4)
Enteral Nutrition (Phase 2/Phase 3)
Febrile Neutropenia (Phase 3)
Fetal Membranes, Premature Rupture (Phase 4)
Fever (Phase 4)
Focal Infection, Dental (Phase 4)
Gastritis (Phase 4)
Gastrointestinal Microbiome (Phase 4)
General Surgery (Phase 4)
Graft Survival (Phase 4)
Hand Injuries (Phase 4)
Healthy Volunteers (Phase 1)
Helicobacter Infections (Phase 4)
Helicobacter pylori (Phase 4)
Incisional Hernia (Phase 3)
Infant, Premature (Phase 4)
Infection Control (Phase 4)
Infections ()
Inflammation (Phase 4)
Influenza, Human (Phase 1)
Intestinal Neoplasms (Phase 4)
Intraabdominal Infections (Phase 3)
Jaw Fractures (Phase 1)
Laparoscopy (Phase 4)
Lung Diseases (Phase 4)
Lymphoma (Phase 3)
Malnutrition (Phase 4)
Mandibular Diseases (Phase 4)
Medicine, Chinese Traditional (Phase 1)
Metronidazole (Phase 4)
Mobility Limitation (Early Phase 1)
Molar, Third (Phase 1/Phase 2)
Myringoplasty (Phase 4)
Neonatal Sepsis (Phase 4)
Neoplasms (Phase 2/Phase 3)
Obstetric Labor, Premature (Phase 4)
Ofloxacin (Phase 4)
Osteomyelitis (Phase 4)
Otitis Media ()
Pain, Postoperative (Phase 3)
Pancreatic Fistula (Phase 2)
Pediatric Emergency Medicine (Phase 4)
Penicillins (Phase 4)
Peptic Ulcer (Phase 4)
Peptic Ulcer Hemorrhage (Phase 3)
Peri-Implantitis (Phase 4)
Periodontal Diseases (Phase 4)
Periodontal Pocket (Phase 3)
Periodontitis (Phase 4)
Pharmacokinetics (Phase 4)
Pharyngitis ()
Pneumonia ()
Pneumonia, Aspiration (Phase 4)
Postoperative Complications (Phase 4)
Postpartum Period (Phase 4)
Pregnancy (Phase 4)
Pregnancy Complications (Phase 4)
Premature Birth (Phase 4)
Primary Prevention (Phase 4)
Prostatic Neoplasms (Phase 4)
Prostatic Neoplasms, Castration-Resistant (Phase 1/Phase 2)
Prostheses and Implants (Phase 4)
Prosthesis-Related Infections (Phase 3)
Proton Pump Inhibitors (Phase 4)
Puerperal Infection (Phase 4)
Rectal Fistula (Phase 3)
Respiratory Aspiration (Phase 4)
Respiratory Tract Infections (Phase 4)
Root Planing (Phase 4)
Salivary Ducts (Phase 4)
Severe Acute Malnutrition (Phase 4)
Short Bowel Syndrome (Phase 1)
Sinusitis ()
Smoking (Phase 3)
Sprains and Strains (Phase 3)
Stomach Neoplasms (Phase 4)
Stomach Ulcer (Phase 4)
Streptococcus pyogenes (Phase 4)
Surgical Wound Infection (Phase 4)
Temporomandibular Joint Disorders (Phase 4)
Therapeutic Equivalency (Phase 1)
Therapeutics (Phase 4)
Tonsillectomy (Phase 1/Phase 2)
Tonsillitis ()
Tooth Diseases (Phase 4)
Tooth Extraction (Phase 4)
Tooth Wear (Phase 4)
Tuberculosis (Phase 3)
Tuberculosis, Pulmonary (Phase 2)
Urinary Bladder Neoplasms (Phase 3)
Urinary Bladder, Overactive (Phase 4)
Vaginitis (Phase 2)
Wound Infection (Phase 4)
Wounds and Injuries (Phase 4)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
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