Active Ingredient History
Interferon gamma is a dimerized soluble cytokine that is the only member of the type II class of interferons. The existence of this interferon, which early in its history was known as immune interferon, was described by E. F. Wheelock as a product of human leukocytes stimulated with phytohemagglutinin, and by others as a product of antigen-stimulated lymphocytes. It was also shown to be produced in human lymphocytes. or tuberculin-sensitized mouse peritoneal lymphocytes challenged with Mantoux test (PPD); the resulting supernatants were shown to inhibit growth of vesicular stomatitis virus. Those reports also contained the basic observation underlying the now widely employed interferon gamma release assay used to test for tuberculosis. In humans, the IFNG protein is encoded by the IFNG gene. Wikipedia
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Granulomatous Disease, Chronic (approved 1999)
Osteopetrosis (approved 2001)
Adenocarcinoma (Phase 1/Phase 2)
AIDS-Related Complex (Phase 2)
Arthritis, Reactive (Phase 2)
Aspergillosis (Phase 2)
Breast Neoplasms (Phase 3)
Breast Neoplasms, Male (Phase 1/Phase 2)
Bronchiolitis (Phase 2)
Candidemia (Phase 3)
Cholecalciferol (Phase 2/Phase 3)
Colonic Neoplasms (Phase 1/Phase 2)
Colorectal Neoplasms (Phase 2)
Critical Illness (Phase 2)
Cystic Fibrosis (Phase 1/Phase 2)
Endoscopy (Phase 2/Phase 3)
Fallopian Tube Neoplasms (Phase 2)
Fibrosis (Phase 2)
Friedreich Ataxia (Phase 3)
Genotype (Phase 2/Phase 3)
Glioblastoma (Phase 1)
Graft vs Host Disease (Phase 3)
Granuloma (Phase 4)
Granulomatous Disease, Chronic (Phase 4)
Hamartoma (Phase 3)
Healthy Volunteers (Phase 2)
Hematopoietic Stem Cell Transplantation (Early Phase 1)
Hepatitis C (Phase 2/Phase 3)
Hepatitis C, Chronic (Phase 2)
HIV (Phase 1/Phase 2)
HIV Infections (Phase 2)
Idiopathic Pulmonary Fibrosis (Phase 3)
Infections (Phase 2)
Influenza, Human (Phase 4)
Interferon-gamma (Phase 4)
Kidney Neoplasms (Phase 2)
Lentivirus Infections (Phase 1/Phase 2)
Leukemia (Phase 1/Phase 2)
Leukemia, Myeloid (Early Phase 1)
Leukocyte-Adhesion Deficiency Syndrome (Phase 2)
Liposarcoma (Phase 2)
Liver Cirrhosis (Phase 2)
Lung Diseases (Phase 3)
Lung Neoplasms (Phase 2)
Lymphoma (Phase 3)
Lymphoma, Non-Hodgkin (Phase 1/Phase 2)
Macrophage Activation Syndrome (Phase 2)
Macula Lutea (Phase 1/Phase 2)
Melanoma (Phase 3)
Meningitis, Cryptococcal (Phase 2)
Mesothelioma, Malignant (Phase 2)
Multiple Myeloma (Phase 2)
Mutation (Phase 4)
Mycobacterium bovis (Phase 2/Phase 3)
Mycobacterium Infections, Nontuberculous (Phase 2)
Myelodysplastic Syndromes (Early Phase 1)
Neoplasms (Phase 2)
Neuroblastoma (Phase 1)
Ophthalmology (Phase 1/Phase 2)
Osteopetrosis (Phase 3)
Osteosarcoma (Phase 1)
Ovarian Neoplasms (Phase 3)
Pancreatic Neoplasms (Phase 2)
Papillomavirus Infections (Phase 3)
Pleural Effusion, Malignant (Phase 1)
Pneumonia (Phase 2)
Pneumonia, Ventilator-Associated (Phase 3)
Preventive Medicine (Phase 4)
Primary Immunodeficiency Diseases (Phase 4)
Prostatic Neoplasms (Phase 1/Phase 2)
Prostatitis (Phase 3)
Pulmonary Fibrosis (Phase 3)
Respiratory Tract Infections (Phase 4)
Retinal Diseases (Phase 1/Phase 2)
Rhabdomyosarcoma (Phase 1)
RNA Virus Infections (Phase 1/Phase 2)
Sarcoma (Phase 1)
Sarcoma, Ewing (Phase 1)
Sarcoma, Synovial (Phase 2)
Sepsis (Phase 3)
Sezary Syndrome (Phase 2)
Shock, Septic (Phase 3)
Tuberculosis (Phase 2)
Tuberculosis, Pulmonary (Phase 2)
Uveitis (Phase 1/Phase 2)
Uveitis, Anterior (Phase 1/Phase 2)
Warts (Phase 3)
Trial | Phase | Start Date | Organizations | Indications |
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