Diseases [C] » Immune System Diseases [C20] » Immunologic Deficiency Syndromes » Primary Immunodeficiency Diseases » Leukocyte-Adhesion Deficiency Syndrome
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Primary Immunodeficiency Diseases » Leukocyte-Adhesion Deficiency Syndrome
Description
Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS, LEUKOCYTE-ADHESION) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterized by abnormal adhesion-dependent functions, especially defective tissue emigration of neutrophils, leading to recurrent infection. MeSH
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Phase 2 Indicated Drugs (1)
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Organization Involved with Other Experimental Indications (1)
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