sulfamethazine Report issue

Small molecule Approved FDA
ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Sulfamethazine is a sulfonamide used to treat a variety of bacterial diseases in animals. It inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthetase (dihydrofolate synthetase).   NCATS

Chemistry

  • SMILES: CC1=CC(C)=NC(NS(=O)(=O)C2=CC=C(N)C=C2)=N1
  • InChIKey: ASWVTGNCAZCNNR-UHFFFAOYSA-N
  • Mol. Mass: 278.33
  • ALogP: 1.48
  • ChEMBL Molecule:
    sulfamethazine  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Discontinued
  • Delivery Methods: Oral
  • Pro Drug: No

Combination drugs

( sulfamethazine, sulfamerazine (Neotrizine), sulfadiazine )

Alternative names

2-(4-aminobenzenesulfonamido)-4,6-dimethylpyrimidine | 2-(4-aminobenzenesulfonamido)-4-methylpyrimidine | 2-(p-aminobenzenesulfonamido)-4,6-dimethylpyrimidine | 2-sulfanilamido-4,6-dimethylpyrimidine | 4,6-dimethyl-2-sulfanilamidopyrimidine | 4-amino-n-(4,6-dimethyl-pyrimidin-2-yl)-benzenesulfonamide | 4-amino-n-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide | 6-(4'-aminobenzol-sulfonamido)-2,4-dimethylpyrimidin | n(1)-(4,6-dimethyl-2-pyrimidinyl)sulfanilamide | n(1)-(4,6-dimethyl-2-pyrimidyl)sulfanilamide | n(1)-(4-methyl-2-pyrimidinyl)sulfanilamide | n-(4,6-dimethyl-2-pyrimidyl)sulfanilamide | (p-aminobenzolsulfonyl)-2-amino-4,6-dimethylpyrimidin | smz | smz-med 454 | sulfadimerazine | sulfadimethyldiazine | sulfadimethylpyrimidine | sulfadimidina | sulfadimidine | sulfadimidinum | sulfametazina | sulfametazyny | sulfamethazine | sulfamethazine sodium | sulfamethazine sodium salt | sulfamethazine (trisulfapyrimidines) | sulfamezathine | sulfamezathine ('s-mez') | sulphadimethylpyrimidine | sulphamethazine

Organizations (10)

Research & Development (0)

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Marketing (10)

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Indications (1)

Approved Indications (1)


 

Communicable Diseases

Experimental Indications - Clinical Trial Phases 1-4 (0)

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