sulfamerazine (Neotrizine) Report issue

Small molecule Approved FDA
ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Sulfamerazine is a sulfonamide antibiotic, which acts by inhibiting folic acid synthesis in bacterias. The primary target of sulfamerazine is believed to be dihydropteroate synthetase. Sulfamerazine (in comination with Sulfadiazine and Sulfamethazine) was used in the US under different names, including the earliest brand of Neotrizine. Nowdays, the drugs containing sulfamerazine are no longer available for use in humans in the US, however, they may be prescribed for veterinary purposes.   NCATS

Chemistry

  • SMILES: CC1=NC(NS(=O)(=O)C2=CC=C(N)C=C2)=NC=C1
  • InChIKey: QPPBRPIAZZHUNT-UHFFFAOYSA-N
  • Mol. Mass: 264.304
  • ALogP: 1.17
  • ChEMBL Molecule:
    sulfamerazine  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Discontinued
  • Delivery Methods: Oral
  • Pro Drug: No

Combination drugs

( sulfamerazine (Neotrizine), sulfadiazine )
|
( sulfamethazine, sulfamerazine (Neotrizine), sulfadiazine )

Alternative names

2-(p-aminobenzolsulfonamido)-4-methylpyrimidine | 2-sulfa-4-methylpyrimidine | 2-(sulfanilamido)-4-methylpyrimidine | 4-amino-n-(4-methyl-2-pyrimidinyl)-benzenesulfonamide | cremomerazine | mesulfa | methylsulfazine | methypyrimal | metilsulfadiazin | n-(4-methyl-2-pyrimidyl)sulfanilamide | (p-aminobenzolsulfonyl)-2-amino-4-methylpyrimidin | sulfamerazin | sulfamerazina | sulfamerazine | sulfamerazine (trisulfapyrimidines) | sulfamerazinum | sulfamethyldiazine | sulphamerazine | sumedin

Organizations (11)

Research & Development (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (11)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (1)

Approved Indications (1)


 

Bacterial Infections

Experimental Indications - Clinical Trial Phases 1-4 (0)

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