avobenzone (shade uvaguard) Report issue

Small molecule Approved FDA
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Avobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays. It helps prevent sunburn. Avobenzone works by absorbing the rays and converting them to energy that is less damaging to the skin.   NCATS

Chemistry

  • SMILES: COC1=CC=C(C=C1)C(=O)CC(=O)C2=CC=C(C=C2)C(C)(C)C
  • InChIKey: XNEFYCZVKIDDMS-UHFFFAOYSA-N
  • Mol. Mass: 310.3869
  • ALogP: 4.45
  • ChEMBL Molecule:
    avobenzone  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Over the Counter
  • Delivery Methods: Topical
  • Pro Drug: No

Combination drugs

( titanium, octocrylene, avobenzone (shade uvaguard), ecamsule (Mexoryl SX) )
|
( octocrylene, avobenzone (shade uvaguard), ecamsule (Mexoryl SX) - other name: capital soleil )
|
( oxybenzone, avobenzone (shade uvaguard), octinoxate )

Alternative names

4-tert-butyl-4'-methoxydibenzoylmethane | avobenzone | butylmethoxydibenzoylmethane | butyl methoxydibenzoylmethane | butyl-methoxy-dibenzoylmethane | parsol 1789 | parsol-1789 | photoplex | shade uvaguard

Organizations (9)

Research & Development (7)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (4)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (7)

Approved Indications (3)


 

Melanosis

Skin Neoplasms

Sunburn (approved 1992)

Experimental Indications - Clinical Trial Phases 1-4 (6)


 

Dermatology (Phase 2/Phase 3)

Melanosis (Phase 4)

Nerve Sheath Neoplasms (Phase 2)

Sunburn (Phase 3)

Sun Protection Factor (Phase 3)

Tumor Suppressor Protein p53 (Phase 2)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 9
  • # of Trial Organizations: 7

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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