oxybenzone Report issue

Small molecule Approved FDA
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Oxybenzone is one of the more popular molecules used by chemists during the manufacturing of cosmetics and is included in sunscreen for UV protection. The chemical is often used to stabilize and strengthen the color and scent of skin care products, but its widest use is in the form of sun block. Unfortunately, the debate about the safety of oxybenzone is still ongoing. One of the biggest concerns in the medical community about the widespread use of the molecule comes from the fact that it’s easily absorbed into the body. This absorption raises concerns that oxybenzone may accumulate in the body, eventually leading to potentially toxic levels of the chemical, which can affect the endocrine system.   NCATS

Chemistry

  • SMILES: COC1=CC=C(C(=O)C2=CC=CC=C2)C(O)=C1
  • InChIKey: DXGLGDHPHMLXJC-UHFFFAOYSA-N
  • Mol. Mass: 228.2433
  • ALogP: 2.63
  • ChEMBL Molecule:
    oxybenzone  
More Chemistry

Pharmacology

  • Mechanisms of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Over the Counter
  • Delivery Methods: Topical
  • Pro Drug: No

Combination drugs

( oxybenzone, avobenzone (shade uvaguard), octinoxate )

Alternative names

2-benzoyl-5-methoxyphenol | 2-hydroxy-4-methoxybenzone | 2-hydroxy-4-methoxybenzophenone | (2-hydroxy-4-methoxyphenyl)phenylmethanone | 4-methoxy-2-hydroxybenzophenone | 4-methoxy-2-hydroxybenzophenone butyric acid | benzophenone-3 | eusolex 4360 | eusolex-4360 | hmbp cpd | oxibenzona | oxybenzon | oxybenzone | oxybenzonum | solbar | uvinul m40

Organizations (3)

Research & Development (3)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (1)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (4)

Approved Indications (2)


 

Melanosis

Sunburn (approved 1992)

Experimental Indications - Clinical Trial Phases 1-4 (3)


 

Dermatology (Phase 1)

Melanoma (Phase 1)

Melanosis (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 3
  • # of Trial Organizations: 3

Trials by Phase

Trial Phase Start Date Organizations Indications

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