Trial | NCT04646278  Report issue

Title

Coronary Hemodynamics by Coronary Angiography
Estimation of Coronary Artery Hemodynamic Profiles Using Cineangiography Technique

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    50
Study for developing techniques to evaluate coronary artery hemodynamic profiles by conventional angiography without more dedicated measuring devices.
* Methods: Compare TIMI frame count, coronary clearance frame count in baseline/hyperemic coronary angiography with FFR, CFR, IMR and derive correlation, receiver-operating characteristic curve to find new tools estimating coronary hemodynamics by conventional angiography only.

A TIMI frame count is measured by counting the angiographic image cine frames during a head of radiocontrast column runs from the entry of left anterior descending artery (LAD) to the distal end.

A coronary clearance frame count is measured by counting the angiographic image cine frames during a tail of radiocontrast column runs from the entry of LAD to the distal end.

Baseline angiography is performed without any stimulation and hyperemic angiography is performed after intracoronary injection of adenosine 300ug or nicorandiol 2mg.

Inclusion criteria

Patient who underwent physiologic study using a pressure wire for intermediate coronary lesion after coronary angiography

Exclusion criteria

ST elevation myocardial infarction
Cardiogenic shock
Congestive heart failure with pulmonary edema
LVEF < 30%
Previous history of coronary revascularization
Chronic total occlusion
3 vessel disease
Target lesion at distal segments or branches
Study Started
Apr 11
2017
Primary Completion
Mar 25
2020
Study Completion
Mar 25
2020
Last Update
Nov 27
2020

Drug Hyperemic stimuli

Hyperemic simuli of coronary flow by adenosine or nicorandil injection

  • Other names: Hyperemia

Hyperemic stimuli Experimental

Hyperemic stimuli of coronary flow by adenosine or nicorandil injection

Criteria 

Inclusion criteria

Patient who underwent physiologic study using a pressure wire for intermediate coronary lesion after coronary angiography

Exclusion criteria

ST elevation myocardial infarction
Cardiogenic shock
Congestive heart failure with pulmonary edema
LVEF < 30%
Previous history of coronary revascularization
Chronic total occlusion
3 vessel disease
Target lesion at distal segments or branches
No Results Posted